Label-Free and Selective Single-Molecule Bioelectronic Sensing with a Millimeter-Wide Self-Assembled Monolayer of Anti-Immunoglobulins
Immunoglobulin M (IgM) single-molecule and label-free detection is demonstrated, for the first time, by means of an electrolyte-gated thin-film transistor. The sensor integrates a millimeter-wide self-assembled monolayer (SAM) that includes trillions of anti-IgM capturing proteins. This adds generality to the already introduced single molecule with a transistor (SiMoT) platform. Besides the extremely high sensitivity, the SAM confers to the SiMoT bioelectronic sensor a high selectivity that i...
Printable and flexible thin-film transistors (TFTs) have gained significant attention over the last few years thanks to their implementation in many different sectors. Beside applications in large-area electronics such as flat displays, sensors and radio frequency identification tags, these devices have been widely investigated for life sciences applications too, including label-free biosensors, systems for drug delivery and implantable platforms. This review highlights the recent advances in...
The double layer capacitance of ionic liquids for electrolyte gating of ZnO thin film transistors and effect of gate electrodes
Electrolyte gated thin film transistors (TFTs) based on sol-gel processed zinc oxide (ZnO) are investigated using imidazolium-based ionic liquids (ILs), namely [bmim][BF4] and [bmim][PF6], as electrolytes. The capacitance of the ILs is determined by means of electrochemical impedance spectroscopy. The frequency dependence of the capacitance measurements indicates that the electric double layers (EDLs) form below 1 kHz. Impedance measurements are also acquired at different gate voltages and th...
Advanced Data Systems for Energy Consumption Optimization and Air Quality Control in Smart Public Buildings Using a Versatile Open Source Approach
This work discusses smart building applications involving the Internet of Things (IoT) which are focused on energy consumption monitoring and forecasting systems, as well as indoor air quality (IAQ) control. Low-cost hardware integrating sensors and open source platforms are implemented for cloud data transmission, data storage and data processing. Advanced data analytics is performed by the seasonal autoregressive integrated moving average (SARIMA) method and a long short-term memory (LSTM) ...
Characterization of Covalently Bound Anti-Human Immunoglobulins on Self-Assembled Monolayer Modified Gold Electrodes
Bioconjugated gold surfaces constitute interesting platforms for biosensing applications. The immobilization of antibodies such as anti-immunoglobulin G and M (anti-IgG and anti-IgM) on gold electrodes via self-assembled monolayers (SAMs) is here studied as a model system for further immunoassays development. The biolayer is characterized by means of X-ray photoelectron spectroscopy (XPS), atomic force microscopy (AFM), a dedicated thin-film transistor (TFT)-based platform and electrochemical...
- 1 Contributo su Rivista2762
Data di pubblicazione
- In corso di stampa12
- 2020 - 2023850
- 2010 - 20191381
- 2000 - 2009382
- 1990 - 1999116
- 1984 - 198921
- GIUSTIZIA CIVILE.COM50
- DIRITTO PUBBLICO COMPARATO ED EUR...39
- INTERNATIONAL JOURNAL OF MOLECULA...32
- RIVISTA DI DIRITTO PROCESSUALE28
- IL PROCESSO25
- INTERNATIONAL JOURNAL OF BUSINESS...24
- GIUSTIZIA CIVILE23
- STATO, CHIESE E PLURALISMO CONFES...23
- Middle Aged16
Accesso al fulltext
- no fulltext2762