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L’iscrizione della notizia di reato nel registro: ordine del PM e adempimenti di segreteria. L’incipit investigativo nel “nuovo” assetto normativo

L’incipit investigativo che si realizza con la iscrizione della notizia di reato è strettamente collegato alla tenuta informatica del relativo registro. Il controllo sul rispetto dei termini investigativi è esposto a erronee indicazioni del dies a quo delle indagini, nei casi in cui si verifichi una discrasia temporale tra ordine di iscrizione della notizia di reato del pubblico ministero e “materiale” registrazione della stessa all’interno del registro informativo. Ne consegue la frustrazion...

Diffuse Large B Cell Lymphoma Arising in Patients with Preexisting Hodgkin Lymphoma

Unlabelled: The metachronic onset of diffuse large B-cell lymphoma (DLBCL) after classic Hodgkin lymphoma (cHL) is a rare event affecting patients' outcomes. However, although several studies have investigated the prognostic role of this event, little is known about a hypothetical common origin of the two different neoplastic cells. Aims: To investigate a possible relationship between DLBCL and cHL, in this retrospective study of 269 patients with newly diagnosed cHL treated at Bari Universit...

Blastic Plasmocytoid Dendritic Cell Neoplasm (BPDCN): Clinical Features and Histopathology with a Therapeutic Overview

: Blastic Plasmacytoid Dendritic Cell Neoplasms (BPDCNs) are a rare, highly aggressive hematological malignant neoplasm that primarily involve the skin, bone marrow, lymph nodes and even extra-nodal sites. The rarity and relative poor description of cases in the literature make it necessary to review and further studies that deeply investigate this entity not only in a histopathological but also molecular field. In August-September 2023, we searched MEDLINE, PubMed and Scopus for randomized c...

Molecular Features and Diagnostic Challenges in Alpha/Beta T-Cell Large Granular Lymphocyte Leukemia

: Large granular lymphocyte leukemia is a rare chronic lymphoproliferative disease of cytotoxic lymphocytes. The diagnosis, according to the WHO, is based on a persistent (>6 months) increase in the number of LGL cells in the peripheral blood without an identifiable cause. A further distinction is made between T-LGL and NK-LGL leukemia. The molecular sign of LGL leukemia is the mutation of STAT3 and other genes associated with the JAK/STAT pathway. The most common clinical features are neu...

Il sistema delle intese e la (futura) legge sulla libertà religiosa

In Italy, religions have the right to exist and operate within the State, with the limits established by the Constitution. This is strictly connected with the autonomy of religions to self-organize themselves according to their own statutes, regardless of the presence of an intesa (which can be roughly translated “understanding”) according to article 8 (paragraph 3) of the Italian Constitution. This means that the absence of an intesa does not infer the absence of relations between minority ...

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