Depending upon the primary tumor site, patients with neuroendocrine tumors frequently present with liver metastases. Liver resection is the only potentially curative treatment option. A complete resection of the hepatic tumor mass is feasible in only 20–57% of patients. The majority of resected patients will develop tumor recurrence within 5 years. Liver transplantation is justified in highly selected patients with nonresectable neuroendocrine liver metastases; however, the risk of posttransplant tumor recurrence is high. Management in centers of expertise should be strongly encouraged in order to enable a multidisciplinary approa
Chirurgische Therapie neuroendokriner.Lebermetastasen – Resektion, Transplantation
Tedeschi M;
2010-01-01
Abstract
Depending upon the primary tumor site, patients with neuroendocrine tumors frequently present with liver metastases. Liver resection is the only potentially curative treatment option. A complete resection of the hepatic tumor mass is feasible in only 20–57% of patients. The majority of resected patients will develop tumor recurrence within 5 years. Liver transplantation is justified in highly selected patients with nonresectable neuroendocrine liver metastases; however, the risk of posttransplant tumor recurrence is high. Management in centers of expertise should be strongly encouraged in order to enable a multidisciplinary approaI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.